Opportunity Information: Apply for RFA OD 17 009
The Tobacco Regulatory Science (R21) funding opportunity (RFA-OD-17-009) is a discretionary federal grant program run through the U.S. Department of Health and Human Services via the National Institutes of Health (NIH), using funds provided by the Food and Drug Administration (FDA) Center for Tobacco Products (CTP) under the Family Smoking Prevention and Tobacco Control Act (Public Law 111-31). Its main goal is to support short, exploratory research projects that produce biomedical and behavioral evidence the FDA can actually use when making regulatory decisions about tobacco products, with the larger purpose of protecting public health. In practice, that means proposals need to be tightly aligned with the FDA CTP's regulatory research priorities and designed to generate data that can inform how tobacco products are made, distributed, and marketed in the United States.
The FOA uses the NIH R21 mechanism, which is typically intended for early-stage, high-impact, or proof-of-concept studies rather than long, multi-year full-scale projects. The emphasis is on producing clear, decision-relevant findings that can help answer questions the FDA faces when regulating tobacco products. Projects under this announcement are expected to lead to results that are directly relevant to FDA authorities, such as how product characteristics, user behaviors, marketing practices, and population-level impacts relate to risk, addiction, exposure, and public health outcomes. The overall expectation is not just general tobacco research, but tobacco regulatory science: research framed so its outputs can support evidence-based regulation.
The opportunity is categorized under Health and corresponds to CFDA number 93.077. The award ceiling listed for this FOA is $200,000, and the program anticipated making about 14 awards. The opportunity was created on May 10, 2017, and the original closing date was February 13, 2019. While those dates indicate the specific announcement cycle, the summary purpose remains useful for understanding what the program sought to fund: research that fills evidence gaps relevant to FDA regulation of tobacco products.
Eligibility is broad and includes many types of organizations that can carry out rigorous research, such as state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other tribal organizations; public housing authorities; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses, with additional eligibility details referenced in the full announcement. This wide eligibility reflects the program's focus on generating usable regulatory evidence rather than limiting participation to a narrow set of academic institutions.
In short, this FOA was designed to fund targeted R21 research projects that produce practical scientific data to help the FDA CTP regulate tobacco products in ways that reduce harm and protect public health, with NIH administering the awards using FDA-provided funds authorized by federal tobacco control law.Apply for RFA OD 17 009
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Tobacco Regulatory Science (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.077.
- This funding opportunity was created on May 10, 2017.
- Applicants must submit their applications by Feb 13, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- The number of recipients for this funding is limited to 14 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs)
What is the Tobacco Regulatory Science (R21) funding opportunity (RFA-OD-17-009)?
This opportunity is a discretionary federal grant program focused on tobacco regulatory science. It uses the NIH R21 research grant mechanism to support short, exploratory projects that generate biomedical and behavioral evidence the FDA can use in regulatory decision-making about tobacco products.
Which federal agencies are involved in this grant program?
The program runs through the U.S. Department of Health and Human Services via the National Institutes of Health (NIH). Funding is provided by the Food and Drug Administration (FDA) Center for Tobacco Products (CTP) under the authority of the Family Smoking Prevention and Tobacco Control Act (Public Law 111-31).
What is the primary goal of this funding opportunity?
The primary goal is to support short, exploratory research that produces decision-relevant scientific evidence the FDA can use when regulating tobacco products, with the broader purpose of protecting public health.
What makes a project "tobacco regulatory science" rather than general tobacco research?
Projects must be framed to produce outputs that are directly useful for FDA CTP regulatory decisions. The emphasis is on filling evidence gaps tied to FDA authorities, rather than conducting tobacco-related research that is not designed to inform regulation.
What kinds of research outputs is the program trying to generate?
The program seeks clear, practical findings that can inform FDA decision-making about how tobacco products are made, distributed, and marketed in the United States, and how these factors relate to risk, addiction, exposure, and population-level public health outcomes.
What types of topics or factors are expected to be relevant to FDA regulatory decisions?
Based on the opportunity description, relevant factors include product characteristics, user behaviors, marketing practices, and population-level impacts, especially where they connect to risk, addiction, exposure, and public health outcomes.
What funding mechanism does this opportunity use?
It uses the NIH R21 mechanism, which is typically intended for early-stage, high-impact, proof-of-concept, or exploratory studies rather than long, multi-year, full-scale projects.
What is the funding amount (award ceiling) for this FOA?
The listed award ceiling for this funding opportunity is $200,000.
How many awards were anticipated under this announcement?
The program anticipated making about 14 awards.
What is the CFDA number associated with this opportunity?
The opportunity corresponds to CFDA number 93.077.
What program area or category does this opportunity fall under?
It is categorized under Health.
When was this funding opportunity created and when did it close?
The opportunity was created on May 10, 2017, and the original closing date was February 13, 2019. Those dates reflect the specific announcement cycle referenced in the provided information.
Who is eligible to apply?
Eligibility is broad and includes: state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other tribal organizations; public housing authorities; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses. Additional eligibility details are referenced in the full announcement.
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) are listed as eligible, and small businesses are also listed as eligible.
Are tribal entities eligible to apply?
Yes. Federally recognized Native American tribal governments and other tribal organizations are included in the eligible applicant types.
Are schools and universities eligible?
Yes. Independent school districts, public and state-controlled institutions of higher education, and private institutions of higher education are included among eligible organizations.
Are nonprofits required to have 501(c)(3) status to apply?
No. The eligibility list includes nonprofit organizations with or without 501(c)(3) status.
What is the role of FDA CTP in this program?
FDA's Center for Tobacco Products provides the funds for the program and sets regulatory research priorities that proposals are expected to align with, so that study results can support FDA regulatory decisions about tobacco products.
What is the role of NIH in this program?
NIH administers the awards using the R21 grant mechanism, with funds provided by FDA CTP.
What legal authority supports the funding for this opportunity?
The funds are provided under the Family Smoking Prevention and Tobacco Control Act (Public Law 111-31).
What is meant by "decision-relevant" findings in the context of this FOA?
It means the research should be designed to produce evidence that can be used by the FDA in real regulatory contexts, such as evaluating how product design, marketing, distribution, or use patterns influence exposure, addiction, risk, and public health impacts.
What is the larger public health purpose of the funded research?
The larger purpose is to protect public health by supporting evidence-based regulation of tobacco products in ways that reduce harm.
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