Opportunity Information: Apply for RFA NS 18 006
The High Impact Neuroscience Research Resource Grants (R24), Funding Opportunity Number RFA-NS-18-006, is a National Institutes of Health (NIH) program under the U.S. Department of Health and Human Services that supports projects aimed at making valuable research resources broadly available to the neuroscience community. The central idea is practical impact: the funded work should improve access to important reagents, tools, techniques, or services that many neuroscientists can use, especially resources that are difficult to obtain, not widely distributed, or not currently available at sufficient scale. Rather than paying primarily for new invention, the program is oriented toward getting high-value resources into the hands of researchers and expanding who can use them.
Projects are expected to focus on one or more of several core activities tied to resource availability and dissemination. This can include facilitating access to cutting-edge reagents or techniques (for example, providing standardized biological materials, specialized assays, or validated protocols), expanding dissemination of existing resources to new user groups (such as enabling broader adoption across institutions, regions, or subfields), or introducing innovative approaches that increase the scale, efficiency, reliability, or speed of producing and delivering resources. In other words, applications should emphasize distribution, access, production, and service to the community, not simply describing a promising tool and leaving it in a single lab.
A key boundary in this announcement is that applications focused mainly on technology development or software development are considered non-responsive. The FOA is not meant to function as a general technology R&D mechanism. However, it does allow for the use of existing technologies when that use leads to the creation of new reagents or genetic lines that would be of significant value to neuroscience researchers. The distinction is that the work should result in tangible, shareable resources (and a credible plan to deliver them), rather than primarily producing a new platform, algorithm, or prototype. Successful projects are also expected to address a compelling need across broad communities of neuroscientists or provide a truly unique service that would otherwise be unavailable, which signals that reviewers will be looking for strong evidence of demand, reach, and community benefit.
All proposed activities must support the mission of the National Institute of Neurological Disorders and Stroke (NINDS), meaning the resource should be relevant to neurological disorders, stroke, and fundamental neuroscience in ways aligned with NINDS priorities. Practically, applicants should be prepared to show how the resource will advance neuroscience research capacity and accelerate discovery for multiple investigators, not just the proposing team. Reviewers would reasonably expect clear plans for distribution and access, quality control, user support or training where appropriate, and operational approaches that ensure the resource can be provided reliably to the community.
The opportunity uses the NIH grant funding instrument under the Health activity category and is associated with CFDA number 93.853. The award ceiling listed is $350,000, with an expected number of approximately five awards. Eligible applicants are broad and include state, county, city/township, and special district governments; public and private institutions of higher education; independent school districts; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding higher education institutions in those categories); for-profit organizations (including small businesses and other for-profits); and other entities as described in the additional eligibility guidance. The posted dates indicate the FOA was created on September 20, 2017, with an original closing date of February 9, 2018, which is important for applicants to verify if any reissues or current equivalents exist if they are looking to apply now.
Overall, this R24 program is best understood as a resource distribution and scaling grant for neuroscience: it supports efforts that take high-value reagents, genetic lines, specialized techniques, or unique research services and make them broadly, efficiently, and reliably accessible to the wider research community, with a strong emphasis on real-world uptake and alignment with the NINDS mission.Apply for RFA NS 18 006
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "High Impact Neuroscience Research Resource Grants (R24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853.
- This funding opportunity was created on Sep 20, 2017.
- Applicants must submit their applications by Feb 09, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $350,000.00 in funding.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs): High Impact Neuroscience Research Resource Grants (R24)
What is the High Impact Neuroscience Research Resource Grants (R24) program?
The High Impact Neuroscience Research Resource Grants (R24) program is an NIH funding opportunity (Funding Opportunity Number RFA-NS-18-006) under the U.S. Department of Health and Human Services. It supports projects that make valuable research resources broadly available to the neuroscience community, with a strong emphasis on practical impact through access, distribution, scaling, and reliable service to many researchers.
What is the main goal of this funding opportunity?
The main goal is to improve access to important neuroscience research resources (such as reagents, tools, techniques, or services), especially when those resources are difficult to obtain, not widely distributed, or not available at sufficient scale. The focus is on getting high-value resources into the hands of researchers and expanding who can use them.
What types of projects does this FOA prioritize?
This FOA prioritizes projects that emphasize real-world availability and dissemination of research resources. Applications are expected to focus on activities like distribution, access, production, scaling, and providing services to the broader neuroscience community, rather than keeping a tool confined to a single lab or limited user group.
What kinds of activities are considered responsive to this announcement?
Projects are expected to focus on one or more core activities tied to resource availability and dissemination, including:
- Facilitating access to cutting-edge reagents or techniques (for example, standardized biological materials, specialized assays, or validated protocols)
- Expanding dissemination of existing resources to new user groups (across institutions, regions, or subfields)
- Introducing innovative approaches that increase scale, efficiency, reliability, or speed of producing and delivering resources
Is this grant intended to fund new invention or early-stage R&D?
No. The program is oriented toward practical impact and broad availability of valuable resources, rather than paying primarily for new invention. It is best understood as a resource distribution and scaling grant for neuroscience.
Are technology development or software development projects allowed?
Applications focused mainly on technology development or software development are considered non-responsive. This FOA is not intended to function as a general technology R&D mechanism.
Can existing technologies be used in a project under this FOA?
Yes. The FOA allows the use of existing technologies when that use leads to the creation of new reagents or genetic lines that would be of significant value to neuroscience researchers. The key expectation is that the work results in tangible, shareable resources, along with a credible plan to deliver them to the community.
What does "practical impact" mean in the context of this opportunity?
"Practical impact" means the project should measurably improve how widely and reliably neuroscience researchers can obtain and use a resource. Reviewers will be looking for strong evidence that the work increases access, expands reach, and provides clear community benefit beyond the proposing team.
Who is the intended beneficiary of the resources supported by this grant?
The intended beneficiaries are broad communities of neuroscientists. The program emphasizes resources and services that many investigators can use, not just the proposing lab or a narrow set of collaborators.
What makes a resource a good fit for this program?
A strong fit is a resource that meets a compelling need across broad neuroscience communities or provides a truly unique service that would otherwise be unavailable. The resource should be difficult to obtain, not widely distributed, or currently not available at sufficient scale, and the project should meaningfully improve access and uptake.
How important is a distribution and access plan?
It is central to the purpose of the FOA. Reviewers would reasonably expect clear plans for distribution and access, including how the resource will reach multiple investigators and how availability will be expanded beyond a single lab or institution.
Are quality control and reliability expectations mentioned in the FOA summary provided?
Yes. Successful projects are expected to include operational approaches that ensure the resource can be provided reliably to the community, and reviewers would reasonably expect plans for quality control.
Does the FOA expect user support or training?
Where appropriate, reviewers would reasonably expect user support or training. This aligns with the goal of ensuring the wider community can reliably access and use the resource or service.
What NIH institute mission must the project support?
All proposed activities must support the mission of the National Institute of Neurological Disorders and Stroke (NINDS). The resource should be relevant to neurological disorders, stroke, and/or fundamental neuroscience in ways aligned with NINDS priorities.
How should applicants demonstrate alignment with NINDS priorities?
Applicants should be prepared to show how the resource will advance neuroscience research capacity and accelerate discovery for multiple investigators, and how it relates to neurological disorders, stroke, and/or fundamental neuroscience consistent with NINDS priorities.
What is the Funding Opportunity Number (FOA number) for this announcement?
The Funding Opportunity Number is RFA-NS-18-006.
What NIH grant mechanism is used?
The opportunity uses the NIH grant funding instrument and is an R24 program focused on high-impact neuroscience research resources.
What is the activity category associated with this opportunity?
The activity category is Health.
What is the CFDA number associated with this opportunity?
The opportunity is associated with CFDA number 93.853.
What is the award ceiling for this funding opportunity?
The listed award ceiling is $350,000.
How many awards are expected?
The opportunity indicates an expected number of approximately five awards.
Who is eligible to apply?
Eligible applicants are broad and include:
- State, county, city/township, and special district governments
- Public and private institutions of higher education
- Independent school districts
- Federally recognized tribal governments and other tribal organizations
- Public housing authorities/Indian housing authorities
- Nonprofit organizations with or without 501(c)(3) status (excluding higher education institutions in those categories)
- For-profit organizations (including small businesses and other for-profits)
- Other entities as described in additional eligibility guidance
Is this opportunity limited to academic institutions?
No. Based on the eligibility list provided, applicants can include government entities, nonprofits, for-profits (including small businesses), tribal governments and organizations, and other eligible entities, in addition to public and private higher education institutions.
What kinds of resources are explicitly mentioned as examples?
Examples mentioned include standardized biological materials, specialized assays, validated protocols, new reagents, genetic lines, specialized techniques, and unique research services that can be made broadly accessible.
What is the difference between a "resource" project and a "technology development" project under this FOA?
The distinction described is outcome and emphasis: a responsive project results in tangible, shareable resources and a credible plan to deliver them broadly. A non-responsive project is one focused mainly on technology development or software development (for example, primarily producing a new platform, algorithm, or prototype rather than distributing a usable resource at scale).
When was this FOA created and what was the original closing date?
The FOA was created on September 20, 2017, and the original closing date was February 9, 2018.
What should someone do if they want to apply now?
Because the dates provided indicate an original closing date of February 9, 2018, applicants should verify whether any reissues or current equivalents exist if they are looking to apply now.
How should applicants think about the overall purpose of this R24 program?
It is best understood as a neuroscience resource distribution and scaling program that supports efforts to make high-value reagents, genetic lines, specialized techniques, or unique research services broadly, efficiently, and reliably accessible to the wider research community, with clear emphasis on real-world uptake and alignment with the NINDS mission.
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