Opportunity Information: Apply for RFA AT 17 003

The Limited Competition: Research Resource for Systematic Reviews of Complementary and Integrative Health (R24) opportunity is a National Institutes of Health (NIH) grant announcement from the National Center for Complementary and Integrative Health (NCCIH) that focuses on continuing support for an already-established research resource: a database that catalogs primary reports of controlled clinical trials across the full range of complementary and integrative health interventions. The central idea is to keep this database robust, current, and usable so that researchers can more easily produce high-quality systematic reviews and, when the evidence supports it, meta-analyses. By gathering and organizing controlled trial reports in one place, the resource is intended to reduce duplication of effort, speed up evidence synthesis, and improve the overall rigor and completeness of reviews in this field.

A key purpose of the program is to strengthen the evidence base for real-world decision-making. Systematic reviews that comprehensively identify and evaluate all relevant controlled trials on a given topic, and then summarize findings using transparent and unbiased methods, are widely treated as a best-available snapshot of what the evidence says at a specific point in time. NCCIH is positioning this resource as a foundation for that kind of evidence synthesis, with the expectation that the resulting reviews will be useful not only to researchers, but also to clinicians, patients, health policy decision-makers, and research administrators who rely on credible summaries of effectiveness and safety when making choices about care, coverage, and research priorities.

Beyond simply maintaining a database, the FOA emphasizes active stewardship of the resource and service to the broader scientific community. Applicants are expected to demonstrate concrete plans to ensure access and availability, meaning the database should be usable by others in the field rather than functioning as a closed or purely internal tool. The announcement also highlights the need to provide editorial, methodological, and technical support to users conducting systematic reviews. In practice, that implies the funded team should have the expertise and infrastructure to help reviewers navigate the database, apply systematic review standards, manage data extraction, and address methodological issues that come up in evidence synthesis.

The application requirements make clear that NCCIH is looking for continuation funding rather than a brand-new build. Applicants must justify why continued NIH support is necessary, explain how the resource will be maintained, and describe how the database and any associated review products will be kept up to date. The FOA specifically calls for ongoing updates of current reviews included in the database, reflecting the reality that systematic reviews can become outdated as new trials are published. The awardee is also expected to produce a steady output of evidence synthesis products tied to NCCIH priorities: at minimum, one new systematic review and updates to two existing NCCIH strategic plan-related systematic reviews each year, with meta-analysis included when feasible and appropriate.

Priority alignment is an explicit selection factor. The funded group must describe the methods they will use to identify which new systematic reviews and which updates should be pursued, and those choices need to track with NCCIH strategic priorities. The announcement singles out a particularly important thematic area: evaluating the effectiveness of mind and body complementary interventions for pain conditions. That indicates the program is not just about archiving trials, but about guiding synthesis efforts toward high-need clinical questions where complementary and integrative approaches are commonly used and where decision-makers want clearer evidence about what works, for whom, and under what circumstances.

From an administrative standpoint, this is a discretionary, grant-funded opportunity under the health funding category (CFDA 93.213) administered by the U.S. Department of Health and Human Services through NIH. It is a limited competition, meaning only a narrow set of applicants are intended to apply, and eligibility is listed as public and state-controlled institutions of higher education. The FOA number is RFA-AT-17-003, it was created June 26, 2017, with an original closing date of August 21, 2017. Funding is relatively focused, with an award ceiling of $400,000 and an expectation of a single award, reinforcing that NCCIH is aiming to support one central, well-maintained national-level resource rather than multiple competing databases.

  • The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition: Research Resource for Systematic Reviews of Complementary and Integrative Health (R24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213.
  • This funding opportunity was created on Jun 26, 2017.
  • Applicants must submit their applications by Aug 21, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $400,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Public and State controlled institutions of higher education.
Apply for RFA AT 17 003

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